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What are the Benefits of St. John Wort for Mild Depression?

John’s Wort has been shown to be effective in mild to moderate depression. It is also comparable to more powerful or toxic antidepressants. It is safe and effective for patients suffering from mild to moderate anxiety or depression. Other reported benefits, such as an antimicrobial agent to treat neuropathy, antiinflammatory, treatment option for atopic skintitis, and antioxidant, are not well documented. Further research is required. St. John’s Wort has an inherent safety margin. Most adverse drug reactions (ADRs), reported to date, are skin reactions. A few isolated, but more serious ADRs have been reported with respect to neurological effects, thyroid function and increased prothrombin times.

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The potential for interactions between St. John’s Wort and mainstream pharmaceuticals via induction of Cytochrome P450 is of greatest concern. Patients who are receiving drugs metabolized via this pathway concurrently should be closely monitored for altered drug effects. Hippocrates’ writings have described St. John’s Wort for thousands of years. St. John’s Wort has been used historically to treat neurological and psychoiatric disorders (anxiety and insomnia, bed-wetting and irritability as well as exitability, exhaustion and fibrositis. It has also been used to treat gastritis and gout. Some forms of the herb can be used topically to treat wounds, blisters, burns and cuts, hemorhoids, vitiligo and neuralgias, inflammation and insect bites.

A typical dosage regimen is 300 mg of Hypericum extract taken three times daily for a period of four to six weeks. Numerous clinical trials have shown the effectiveness of St.John’s Wort in treating depression. There were 34 controlled trials that included more than 3000 patients by the spring 2002. Comparing the synthetic antidepressants, there were four trials with amitriptyline and four with imiprimine. Two with fluoxetine, two each with sertraline and bromazepam. One trial with maprotiline was also conducted.


Hypericum was superior to all other antidepressants except amitriptyline in all these trials. In mild to moderate depression, hypericum was found to be superior to placebo. The results of trials on patients with mild to moderate depression seem encouraging, but there are limitations. The longest trial was 56 days long, and some trials were only 28 days. The majority of trials used low doses synthetic antidepressants. Two trials didn’t give the exact number of respondents, making the results a little questionable. It is unknown what the exact mechanism of St. John’swort’s neurological effects are. It is also not known if one chemical component is responsible for the activity or if it is a combination.

St. John’s Wort has been used topically to heal wounds for hundreds of years. As early as 1959, antibacterial properties were reported. Hyperforin was identified as the active component. It has been confirmed that both the pseudohypericin and hypericin components of St. John’s Wort have antiviral properties. The trial involved 47 patients. There was a trend toward less total pain after the St. John’swort treatment, but it wasn’t statistically significant. People reported varying degrees of pain relief after treatment with St. John’s Wort.


The study population was further divided into patients with and those without diabetes. It was found that the 18 participants with diabetes had a tendency toward lower total pain and a significant decrease in lancinating pain. However, the 29 participants who did not have diabetes showed no significant differences in their pain scores. It was interesting to note that 25 participants preferred the St. John’swort treatment arm, 16 preferred placebo and six didn’t have a preference. One patient who was taking 1800 mg three times daily over 32 days stopped her treatment due to a possible photosensitivity reaction.

Within one day, she experienced nausea, anorexia and retching. She also developed dry mouth, dizziness, dizziness, dry lips, chills, extreme fatigue, and dry mouth. The symptoms began to improve over the next day, and then they became severe by the eighth day. Many patients who have taken St. John’s Wort have reported elevated levels of thyroid-stimulating hormonal (TSH). A man who took St. John’s wort for nine months reported a severely decreased libido. This was resolved when he stopped taking St. John’s wort and started citalopram. Hair loss has also been linked to St. John’s Wort. After five months of treatment, a 24-year-old woman who took 300mg of St. John’s Wort three times daily noticed a loss in her eyebrows and scalp. The hair loss continued for 12 months. St John Wort can have side effects so be careful and consult your physician. It can be used in moderation and could be considered an alternative to phamacuetical medications.

Looking Good

Your hair is the feature that makes your face shine. It is a style element that adds style to your body. What if your hair is falling out? It will be terrible. You can give your hair a completely new look by styling it differently. This can change your outlook on life. Hair is an important and essential part of our lives. Good hair makes you feel good. If one doesn’t look good due to hair loss, it is likely that he will feel depressed. This could lead to depression, anxiety, low self-confidence, isolation, and even loneliness. This can have a negative impact on one’s happiness. Hair loss can be caused by many factors. One reason could be a lack of vitamins.

Hair fall can also occur if you have been sick for more than three to four months. Hair fall can also occur if you have had any surgery. Hormonal problems can also cause hair loss. If the thyroid gland is underactive or overactive, hair can fall out. Thyroid disease treatment can help. Hair loss can occur if the hormones androgens (male hormones) or estrogens (female hormones) are out of balance. Hair loss can be stopped if the hormonal imbalance is corrected. Women often lose their hair around three months after having a baby. This is not only related to hormones. You may also experience traction alopecia (pronounced al-oh-peesha) if you wear cornrows or pigtails, or use tight hair rollers. If the pulling stops, the hair can be restored to its original position.

Hair Loss

Hair loss can also be caused by certain medicines. Your hair may also be affected by medications for gout, blood thinners, chemotherapy for cancer treatment, excessive vitamin A and antidepressants. If you feel that your hair is falling out after taking the medicine, consult your doctor. Most of the time, hair will grow back if you stop taking the medicine. Hair loss can also be caused by infections. Fungal infections can lead to hair fall in children. For such hair loss, antifungal medications may be the best option. Losing hair could also be a sign of an underlying condition, such as diabetes or lupus. It is important to understand the cause of hair loss, as it can often be a sign of underlying disease. You should go to the doctor. A scalp biopsy or blood test may indicate the need for treatment.


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