The main difference between natural healing remedies and those in the Physician’s Desk Reference is the fact that the Physician’s Desk Reference has double blind research and studies listing which dosages cause which side effects. Many herbal remedies do not have this standard. Fortunately, most herbal remedies have side effects that are not as severe as those found in the Physician's Desk Reference. It is not clear whether some herbs are able to produce the placebo effect. There are many…