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What are Monosodium Urate Crystals?

Monosodium Urate Crystal, (MSU), is what causes painful gouty inflammation in many adult males. Gout sufferers don’t know much about their condition. They know that gout is caused by high blood uric acids and must reduce their intake of high-purine diets to prevent another attack. Gout patients take drugs during a gout attack for pain relief and anti-inflammatory purposes. None of the gout medications actually target the monosodium Urate crystals that cause the inflammation.


Even after the inflammation subsides, the urate crystals remain in the synovial fluid and can deposit on the cartilage layers. Painful gout attacks will return whenever there is new monosodium-urate crystal formation. As more urate crystals are formed in the joint, the frequency and intensity of attacks will increase. To cure gout permanently, it is necessary to understand how monosodium-urate crystals form in the synovial fluid. Only then can you reverse the process and remove the urate crystals from the joint.

Purine is the first step in this journey. Although purine is often thought to be derived from food, up to 85% are actually produced by your own body. Millions of cells in our bodies die every day and the DNA within them breaks down, releasing billions of units of purine. Some purines will be used to create new DNA, while the majority must be sent to liver for degrading.

Liver Health

After the liver has broken down the purines into uric acid, the acids will be released into your bloodstream and carried to the kidneys for elimination through urination. Problems can develop when the kidneys are understaffed and the body doesn’t drink enough water to flush out the acids and urea. The kidneys eventually become weaker and the rate of uric acid disposal decreases. This will lead to a buildup of uric acid in your bloodstream.

However, when the pH of your blood reaches alarming levels, the body must find other ways to eliminate the acids. The acid will be ejected from the bloodstream into interstitial fluid, and the acid molecules will slowly seep into the synovial liquid. Crystallization occurs when the concentration of uric acids in the synovial fluid exceeds the saturation point. This is when the monosodium-urate crystals form in the synovial liquid. Now that you understand the path of uric acid, it is possible to reverse the process and melt the urate crystals slowly away.


To flush out the acid from the blood, you should first strengthen your kidney function. As the blood acid level drops, more acid can reabsorbed from the synovial fluid and interstitial fluid. Finally, gout will disappear if the concentration of uric acid in the synovial fluid drops. It takes time!


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