Gout is one of the most manageable forms of arthritis. It is possible to get medications that reduce inflammation and prevent future attacks. Researchers continue to make improvements that allow people with gout to live well. These advances may one day prevent this very painful disease. Gout can be treated with many medications. Doctors are still trying to figure out which ones are most effective and which dosages are best.
Research
Recent studies have compared effectiveness of NSAIDs in treating pain and inflammation associated with gout. They also looked at the optimal dosages for colchicine (a uric acid-lowering drug) and allopurinol (a NSAID-lowering drug) to prevent and control painful attacks. Recent studies have demonstrated promise for a number of new therapies. These include Remicade (infliximab) and other biologic agents that block the chemical tumor necrosis factors.
This chemical is thought to be involved in the inflammation of gout. Febuoxostat is another new drug therapy. It works by blocking an enzyme that produces uric acid.
Proper Diet
Discovering the Role of Foods. Gout is the only form of arthritis where certain foods can worsen symptoms. Research suggests that certain foods may be able to prevent gout. A study published in The New England Journal of Medicine found that men who consume low-fat dairy products have a half-off chance of developing gout. This protective effect is still unknown.
Another study that examined the effects of vitamin C upon uric acids suggests that vitamin C may be beneficial in the prevention or management of gout and other conditions that are related to uric acids production. We are looking for new treatment approaches. Scientists are also studying how different types of cells contribute to gout’s chronic and acute joint manifestations.
Conclusion
This research aims to better understand how urate crystallines activate white blood cells called neutrophils, leading in acute gout attacks; how chronic gout affects the immune system; and how urate crystals interact with bone cells in such a way that chronic gout can cause debilitating bone lesion. It is hoped that an improved understanding of the various inflammatory reactions in gout will lead to new treatment options.