Gout is caused by a combination of prolonged elevations of uric acid levels and overall acidity of the bloodstream. Gout is most common in the big toe (approximately 75% of first attacks), but it can also affect other joints like the ankle, heel and instep, knees, wrist, elbow, fingers and spine. Gout is caused by crystals of uric acids, in the form monosodium-urate, that precipitate on the articular cartilage, tendons, and surrounding tissues. Gout can be primary (including idiopathic) or secondary to another condition.
Gout
Gout is more common among wealthy societies because of a diet high in alcohol, fat, and proteins. Gout can also be a co-morbidity with other diseases such as polycythaemia and intake of cytotoxics. Gout is a common complication of a few solid organ transplants. Gout can be caused by potassium-losing agents such as fasting, surgery, or potassium losing diuretics. Gout is a form arthritis that affects mostly middle-aged and postmenopausal men. Gout is caused by an over-production of uric acid. Gout is one of the most common medical conditions recorded in history.
Gout arthritis is characterized by severe joint pain and rapid inflammation. Gout sufferers are advised to cut down on their intake of purine-rich food. Lifestyle changes and medication can help to prevent or control gout attacks. Gouty joints are the most visible sign of inflammation among all 100 types of arthritis. Gout is a painful form of arthritis that is caused by the accumulation of uric acid crystals around and in the joints.
Uric Acid
Gout is caused when uric acid crystals build up in the tissues. This causes recurrent episodes of joint inflammation. Gout and pseudo-gout are similar in certain ways, but different in others. Gout attacks can often be prevented or controlled by lifestyle and diet changes, as well as the use of medications. Gouty arthritis refers to a form of metabolic disease that causes uric acid deposits in the joints.
Gout was once called “the disease of kings” or “the king among diseases”. Gout is a leading cause of chronic, painful, and disabling arthritis. Gout is one of the most severe forms of arthritis. Gout can be caused by either elevated uric acid or acidity alone. Gout can develop in the small toe joints if the toes have become immobile from an impact injury. Hyperuricemia increases the likelihood of crystallization of uric acid, but it is 10 times more common in patients without clinical gout. Gout can also be caused by normal serum uric acid levels or abnormally low levels (hypouricemia). Paradoxically, acute gout attacks can also occur with a sudden drop in serum uric acid. This could be due to the use of drugs (uricosurics or xanthine oxide inhibitors) or total parenteral nourishment.
Final Fact
Gout is a condition that affects about 10% of hyperuricemia patients. Gout can be caused by alcohol intake and hereditary factors. Gouty people are more likely to be overweight, which can make them more susceptible to hypertension and diabetes. Gout can be found in the poorest classes, who consume a lot of alcohol and eat insufficient quantities.